sinnonhyeon-rejuran-hb-pain-guide

The line I hear most often during Rejuran HB consultations is, "I came because I heard it hurts less." The expectation is that because lidocaine is mixed in, it won't hurt. But the picture we see in the exam room is a little different. A product's ingredients are only the starting point; the pain you actually feel and how satisfied you are often come down to how the skin is read before the procedure and how the pain-support process is layered on. Today, for those hesitating over Rejuran HB because of pain, I want to walk through the two things we check before the product itself, from the perspective of the exam room.

Rejuran HB belongs to the skinbooster family, adding hyaluronic acid and lidocaine to the PN (polynucleotide) of the original Rejuran. It shares the approach of injecting active ingredients directly into the skin, but its purpose differs from procedures that fill volume or change facial contours. Its direction is, above all, toward refining conditions within the skin texture itself, such as dryness and fine lines.

So the cases where we bring up this procedure in the exam room usually sort out like this.

• Skin that is dry and rough, where makeup tends to sit on top
• Cases where the stinging of the original Rejuran felt burdensome and a different approach was wanted
• Cases where fine lines or deep dryness are a concern but a strong procedure is not desired

There is one thing I want to point out here, though. Rejuran HB is not a procedure that ends once you simply inject it. Even within the same face, the forehead, the area around the eyes, the cheeks, around the mouth, and the chin each differ in skin thickness and sensitivity, so the process of examining region by region can influence the quality of the result. Thin, mobile areas like around the eyes or the mouth require more delicacy, while broad areas like the cheeks require attention to both injection spacing and balance.

This is exactly why it is hard to give a flat answer to the question, "Rejuran HB has lidocaine in it, so it won't hurt, right?" Lidocaine can play a supporting role in relieving pain during the procedure, but what you actually feel varies with your skin thickness, sensitivity, how tense you are that day, and the treatment area. In particular, areas where the skin is thin or close to bone, like around the eyes, the mouth, and the forehead, can sometimes react more sensitively to pain.

Placing the original Rejuran and Rejuran HB side by side from the ingredient perspective sorts out like this.

The table shows that Rejuran HB is indeed designed, on the ingredient side, to lower the burden of pain. Still, you have to see it together with the point that the product alone does not settle pain, and that the supportive care layered on during the procedure is what governs what you actually feel. How pain in the Rejuran family is read is covered in the same vein in an article that revisits, from the exam room, the idea that the more it hurts the better Rejuran is.

To carry out Rejuran HB carefully, the first thing we look at is the skin condition of the entire face. Grasping in advance which areas are especially dry and where fine lines stand out helps reduce situations where a certain area gets overloaded or, conversely, where the area of concern ends up underserved.

At On Clinic, before the procedure we check the skin condition and areas of concern with 'Muse,' a skin analyzer equipped with AI functionality, and then design the treatment range and injection method with the balance of the whole face in mind. Because this is a procedure in which many small injections follow one after another, the process of approaching it while checking the condition region by region matters more than finishing quickly. Adjusting injection depth and spacing according to each person's skin thickness and sensitivity is also decided here.

If you are curious about how the approach is divided region by region, an article on the criteria for choosing a skinbooster, which lays out when a skinbooster is brought out first for fine lines around the eyes and forehead, is also worth referring to. If pain worries you and you have many things to ask before starting, you can sort them out in advance through getting a consultation via chat now.

The second checkpoint is not only looking at the product's characteristics, but also considering supportive care that lowers the burden of pain during the procedure. The sequence we actually layer on in the exam room goes roughly like this.

1. Before the procedure, cryo-anesthesia lowers the skin's sense of irritation. The cold temperature temporarily numbs the treatment area, which can be used in a supporting role to reduce the stinging or heat felt during injection.
2. During the procedure, we also use a vibrating device as needed. Vibratory stimulation disperses focus away from injection pain, which can help ease discomfort during the procedure.
3. Given the nature of a procedure that injects densely across many areas of the face, these two steps work in a direction that lowers both psychological tension and the sensation of pain together.

Because the Rejuran family is injected directly into the skin, it is hard to say there is no pain at all. So rather than relying only on the expectation that the product hurts less, it is more realistic to also look at how processes like cooling and vibration are layered on. In the same context, how summer oil-water imbalance and Rejuran are designed in sequence can be followed in an article laying out the design sequence for oil-water imbalance and Rejuran.

After a Rejuran HB procedure, depending on the individual, embossing (small bumps at the injection sites), redness, a burning sensation, swelling, bruising, and the like can appear. These are common reactions that can occur after an injection procedure and mostly ease over time, but the degree of discomfort and how long it lasts vary with each person's skin condition.

At On Clinic, we help the skin settle more comfortably with care that soothes the irritated skin and lowers heat after the procedure. Because management right after the procedure can influence the recovery experience, it is important not to skip soothing care.

Rarely, inflammation, infection, allergic reactions, and the like can appear, so if abnormal symptoms persist or worsen, it is safer to visit promptly and have your condition checked rather than judging on your own. To sum up, Rejuran HB has the potential to lead to a more satisfying experience when the product's characteristics, together with pre-procedure skin reading, region-tailored approach, pain-support care, and post-procedure soothing management, all interlock. If skin texture or deep dryness is a concern and pain worries you, I recommend first checking your current skin condition and then arranging a consultation in a way that suits you. If you are also weighing cheek hollowing and lifting, taking a look at an article on the criteria for checking cheek hollowing in Sinnonhyeon AllTight lifting will also help you set a direction.

How is Rejuran HB different from the original Rejuran?

Rejuran HB is a product in which hyaluronic acid and lidocaine are added to the PN ingredient of the original Rejuran. Hyaluronic acid can act on skin moisturization and lidocaine can act in a supporting role in relieving pain during the procedure, so those who found the pain of the original Rejuran burdensome sometimes consider it.

How painful is the Rejuran HB procedure?

Because it is injected directly into the skin, it is hard to say there is no pain at all. The degree of pain varies with each person's skin thickness, sensitivity, level of tension, and the treatment area. Supportive care such as cryo-anesthesia and the use of a vibrating device can help lower the burden.

What reactions can appear after the procedure?

Depending on the individual, embossing, redness, a burning sensation, swelling, bruising, and the like can appear. Most ease over time, but the degree and duration vary from person to person. If abnormal symptoms persist or worsen, it is necessary to have them checked by a medical professional.

Why is skin condition checked before the procedure?

Because skin thickness and sensitivity differ by area even within the same face. Grasping in advance which areas are dry and where fine lines stand out lets us adjust injection depth and spacing appropriately and build a plan that sufficiently reflects the areas of concern.

For which skin concerns can it be considered?

It can be considered by those whose concerns are declining skin texture, deep dryness, fine lines, and a rough condition. Because it is a procedure focused on condition management itself rather than volume supplementation or changing facial contours, it is best to confirm through a pre-procedure consultation whether it fits your purpose.

Because Rejuran HB is a skinbooster injected directly into the skin, right after the procedure the injection sites may show embossing (small bumps), redness, swelling, a tingling sensation, and, rarely, bruising. Embossing tends to settle as the injected ingredients are absorbed, and redness or tingling often fade within a few days, though the duration and degree vary from person to person. On the day of the procedure, avoiding activities that add heat and irritation, such as hot saunas, intense exercise, and alcohol, and focusing on soothing and moisturizing care can make the recovery experience more comfortable. If swelling or redness lasts longer than expected or pain worsens, it is safer to visit and have your condition checked rather than judging on your own.

The cost of Rejuran HB is not decided simply by "how many cc." It varies with the treatment range (whether the whole face or a partial area like around the eyes and forehead), the amount and number of sessions of product used, and whether pain-support steps such as cryo-anesthesia and vibration and post-procedure soothing care are included. The composition can change the more the face is divided into several areas for dense injection, or the more it is designed together with other skinboosters or procedures. So the exact cost is most accurately given during a consultation, after your skin condition and desired range are checked. Rather than deciding based only on an advertised lowest price, we recommend confirming what is included in the amount.

On Clinic is located in Sinnonhyeon (Gangnam), within easy walking distance of Gangnam Station and Sinnonhyeon Station. For those considering the procedure during a visit to Korea, consultation and interpretation support in multiple languages are available; since checking the skin condition before the procedure and designing region by region matter for Rejuran HB, organizing your areas of concern and worries about pain before your visit makes the consultation smoother. For reservations and inquiries in advance, leave us a message via getting a consultation via chat now, and we will guide you in line with your travel schedule.

Written by: Dr. Oh Seung-min (Chief Director of On Clinic, graduate of Seoul National University College of Medicine, Chair of the Academic Committee of the Korean Society for Laser Dermatology and Trichology). Detailed credentials can be checked at Meet the medical team.

First published 2026-06-09 / Last reviewed 2026-07-09

This article is intended for general informational purposes, and the treatment and results suited to an individual may vary depending on their condition.